TB Phylogeographic Diversity Sequencing Project
Different M. tuberculosis (TB) strains have varying virulence, immunogenicity, and drug resistance. However, currently sequenced T B genomes are thought to be responsible for only a minority of global TB burden.
This project, led by Sebastien Gagneux and Peter Small in collaboration with the NIAID-funded Broad Genomic Sequencing Center for Infectious Disease, exploits recently revealed TB global population structure to re-sequence 25 rationally selected TB strains as representatives of the TB global diversity and identify sequence polymorphisms between these strains.
Polymorphisms are searchable through the links below.
|Multiple Alignment of Diversity Sequencing Data|