Rv2031c - heat shock protein hspX


Protein Domains

Gene Information
LocusRv2031c
SymbolhspX
Gene Nameheat shock protein hspX
Location2278498 - 2278932 (-)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:435 bp
Protein:145 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number29267
Related GenesAcel_0160 Mkms_1098 MSMEG_3932 MT2090 Mvan_1374 nfa8400 PPA0737
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
Search for regulators of Rv2031c
Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionRegulatory Rv2069activeashwinigbhat2012-10-05
Co-expression (Functional linkage)
R. Sun, PJ. Converse et al. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 2004
InteractionRegulatory Rv2069activepriti.priety2012-10-05
Co-expression (Functional linkage)
R. Sun, PJ. Converse et al. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 2004
InteractionRegulatory Rv2034activepriti.priety2012-10-05
Bacterial one-hybrid system
M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
InteractionRegulatory Rv2032activepriti.priety2012-10-05
Spectrophotometric analysis
A. Purkayastha, LA. McCue et al. Identification of a Mycobacterium tuberculosis putative classical nitroreductase gene whose expression is coregulated with that of the acr aene within macrophages, in standing versus shaking cultures, and under low oxygen conditions. Infect. Immun. 2002
InteractionSignaling Rv3133cactivepriti.priety2012-10-05
affinity purification
A. Demissie, EM. Leyten et al. Recognition of stage-specific mycobacterial antigens differentiates between acute and latent infections with Mycobacterium tuberculosis. Clin. Vaccine Immunol. 2006
InteractionSignaling Rv3133cactivepriti.priety2012-10-05
affinity purification
M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
InteractionRegulatory Rv2007cactiveprabhakarsmail2012-10-05
co-expression(Functional linkage)
A. Kumar,JC. Toledo,RP. Patel,JR. Lancaster,AJ. Steyn Mycobacterium tuberculosis DosS is a redox sensor and DosT is a hypoxia sensor. Proc. Natl. Acad. Sci. U.S.A. 2007
InteractionRegulatory Rv2007cactiveakankshajain.212012-10-05
co-expression(Functional linkage)
A. Kumar,JC. Toledo,RP. Patel,JR. Lancaster,AJ. Steyn Mycobacterium tuberculosis DosS is a redox sensor and DosT is a hypoxia sensor. Proc. Natl. Acad. Sci. U.S.A. 2007
InteractionRegulatory Rv1997activejgalag2012-10-05

authors,H. Ohno,G. Zhu,VP. Mohan,D. Chu,S. Kohno,WR. Jacobs,J. Chan The effects of reactive nitrogen intermediates on gene expression in Mycobacterium tuberculosis. Cell. Microbiol. 2003
InteractionRegulatory Rv1997activejgalag2012-10-05

D. Agranoff & S. Krishna Metal ion transport and regulation in Mycobacterium tuberculosis. Front. Biosci. 2004
InteractionRegulatory Rv1997activejgalag2012-10-05

MA. Florczyk, LA. McCue et al. A family of acr-coregulated Mycobacterium tuberculosis genes shares a common DNA motif and requires Rv3133c (dosR or devR) for expression. Infect. Immun. 2003
InteractionRegulatory Rv1996activepriyadarshinipriyanka20012012-10-05
Co-expression (Functional linkage)
authors,SM. Hingley-Wilson,KE. Lougheed,K. Ferguson,S. Leiva,HD. Williams Individual Mycobacterium tuberculosis universal stress protein homologues are dispensable in vitro. Tuberculosis (Edinb) 2010
InteractionRegulatory Rv1996activepriyadarshinipriyanka20012012-10-05
Co-expression (Functional linkage)
MA. Florczyk, LA. McCue et al. A family of acr-coregulated Mycobacterium tuberculosis genes shares a common DNA motif and requires Rv3133c (dosR or devR) for expression. Infect. Immun. 2003
InteractionRegulatory Rv0757activesinghpankaj21162012-10-05
Structural Analysis
J. Gonzalo-Asensio, S. Mostowy et al. PhoP: a missing piece in the intricate puzzle of Mycobacterium tuberculosis virulence. PLoS ONE 2008
InteractionRegulatory Rv0757activesinghpankaj21162012-10-05
Spectrophotometric
J. Gonzalo-Asensio, S. Mostowy et al. PhoP: a missing piece in the intricate puzzle of Mycobacterium tuberculosis virulence. PLoS ONE 2008
InteractionRegulatedBy Rv0348activeyamir.moreno2012-10-05
Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
B. Abomoelak, EA. Hoye et al. mosR, a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis. J. Bacteriol. 2009
InteractionRegulatedBy Rv3681cactiveyamir.moreno2012-10-05
One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. .
M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
InteractionRegulatedBy Rv3678cactiveyamir.moreno2012-10-05
One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. .
M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
InteractionRegulatedBy Rv3416activeyamir.moreno2012-10-05
One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. .
M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
InteractionRegulatedBy Rv3133cactiveyamir.moreno2012-10-05
One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. .
M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
InteractionRegulatedBy Rv2034activeyamir.moreno2012-10-05
One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. .
M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
InteractionRegulatedBy Rv0445cactiveyamir.moreno2012-10-05
One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. .
M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
InteractionRegulatedBy Rv3133cactiveyamir.moreno2012-10-05
Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support.
G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
InteractionRegulatedBy Rv2069activeyamir.moreno2012-10-05
Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support.
G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008