Rv0915c - PPE family protein

Expression: Most Significant Conditions for Rv0915c

Protein Domains

Gene Information
Locus	Rv0915c
Symbol	PPE14
Gene Name	PPE family protein
Location	1020058 - 1021329 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1272 bp Protein:424 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	11427
Related Genes	MT0940 MUL_4463
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0915c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0915c Transcript 1
MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGP
AAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSL
VAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPA
AAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGS
AQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSS
ATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGA
DPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGN
PPR*

Genomic Sequence

>Rv0915c
ATGGATTTCGGGCTTTTACCTCCGGAAGTGAATTCAAGCCGAATGTATTCCGGTCCGGGG
CCGGAGTCGATGCTAGCCGCCGCGGCCGCCTGGGACGGTGTGGCCGCGGAGTTGACTTCC
GCCGCGGTCTCGTATGGATCGGTGGTGTCGACGCTGATCGTTGAGCCGTGGATGGGGCCG
GCGGCGGCCGCGATGGCGGCCGCGGCAACGCCGTATGTGGGGTGGCTGGCCGCCACGGCG
GCGCTGGCGAAGGAGACGGCCACACAGGCGAGGGCAGCGGCGGAAGCGTTTGGGACGGCG
TTCGCGATGACGGTGCCACCATCCCTCGTCGCGGCCAACCGCAGCCGGTTGATGTCGCTG
GTCGCGGCGAACATTCTGGGGCAAAACAGTGCGGCGATCGCGGCTACCCAGGCCGAGTAT
GCCGAAATGTGGGCCCAAGACGCTGCCGTGATGTACAGCTATGAGGGGGCATCTGCGGCC
GCGTCGGCGTTGCCGCCGTTCACTCCACCCGTGCAAGGCACCGGCCCGGCCGGGCCCGCG
GCCGCAGCCGCGGCGACCCAAGCCGCCGGTGCGGGCGCCGTTGCGGATGCACAGGCGACA
CTGGCCCAGCTGCCCCCGGGGATCCTGAGCGACATTCTGTCCGCATTGGCCGCCAACGCT
GATCCGCTGACATCGGGACTGTTGGGGATCGCGTCGACCCTCAACCCGCAAGTCGGATCC
GCTCAGCCGATAGTGATCCCCACCCCGATAGGGGAATTGGACGTGATCGCGCTCTACATT
GCATCCATCGCGACCGGCAGCATTGCGCTCGCGATCACGAACACGGCCAGACCCTGGCAC
ATCGGCCTATACGGGAACGCCGGCGGGCTGGGACCGACGCAGGGCCATCCACTGAGTTCG
GCGACCGACGAGCCGGAGCCGCACTGGGGCCCCTTCGGGGGCGCGGCGCCGGTGTCCGCG
GGCGTCGGCCACGCAGCATTAGTCGGAGCGTTGTCGGTGCCGCACAGCTGGACCACGGCC
GCCCCGGAGATCCAGCTCGCCGTTCAGGCAACACCCACCTTCAGCTCCAGCGCCGGCGCC
GACCCGACGGCCCTAAACGGGATGCCGGCAGGCCTGCTCAGCGGGATGGCTTTGGCGAGC
CTGGCCGCACGCGGCACGACGGGCGGTGGCGGCACCCGTAGCGGCACCAGCACTGACGGC
CAAGAGGACGGCCGCAAACCCCCGGTAGTTGTGATTAGAGAGCAGCCGCCGCCCGGAAAC
CCCCCGCGGTAA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Signaling Rv0916c	active	soumisengupta	2012-10-05
	Co-expression (Functional Linkage) MI. Voskuil,D. Schnappinger,R. Rutherford,Y. Liu,GK. Schoolnik Regulation of the Mycobacterium tuberculosis PE/PPE genes. Tuberculosis (Edinb) 2004
Interaction	Signaling Rv0916c	active	soumisengupta	2012-10-05
	Co-expression (Functional Linkage) authors,NC. Gey van Pittius,SL. Sampson,H. Lee,Y. Kim,PD. van Helden,RM. Warren Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions. BMC Evol. Biol. 2006
Interaction	Signaling Rv0916c	active	soumisengupta	2012-10-05
	Co-expression (Functional Linkage) YA. Skeiky, PJ. Ovendale et al. T cell expression cloning of a Mycobacterium tuberculosis gene encoding a protective antigen associated with the early control of infection. J. Immunol. 2000
Interaction	Signaling Rv0916c	active	soumisengupta	2012-10-05
	Co-expression (Functional Linkage) authors,M. Strong,MR. Sawaya,S. Wang,M. Phillips,D. Cascio,D. Eisenberg Toward the structural genomics of complexes: crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U.S.A. 2006
Interaction	Signaling Rv0916c	active	soumisengupta	2012-10-05
	Co-expression (Functional Linkage) MI. Voskuil,D. Schnappinger,R. Rutherford,Y. Liu,GK. Schoolnik Regulation of the Mycobacterium tuberculosis PE/PPE genes. Tuberculosis (Edinb) 2004
Interaction	Signaling Rv0916c	active	soumisengupta	2012-10-05
	Co-expression (Functional Linkage) authors,NC. Gey van Pittius,SL. Sampson,H. Lee,Y. Kim,PD. van Helden,RM. Warren Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions. BMC Evol. Biol. 2006
Interaction	Signaling Rv0916c	active	soumisengupta	2012-10-05
	Co-expression (Functional Linkage) YA. Skeiky, PJ. Ovendale et al. T cell expression cloning of a Mycobacterium tuberculosis gene encoding a protective antigen associated with the early control of infection. J. Immunol. 2000