Rv2612c - phosphatidylinositol synthase pgsA1

Expression: Most Significant Conditions for Rv2612c

Protein Domains

Gene Information
Locus	Rv2612c
Symbol	pgsA1
Gene Name	phosphatidylinositol synthase pgsA1
Location	2939959 - 2940612 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:654 bp Protein:218 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	24782
Related Genes	Acel_1355 CE1783 cg1878 DIP1386 jk1064 MAP2714c MAV_3488 Mkms_2291 ML0454 Mmcs_2244 MSMEG_2933 MT2687 MUL_3254 Mvan_2560 nfa37100 PPA1078 SAV6826
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2612c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2612c Transcript 1
MSKLPFLSRAAFARITTPIARGLLRVGLTPDVVTILGTTASVAGALTLFPMGKLFAGACV
VWFFVLFDMLDGAMARERGGGTRFGAVLDATCDRISDGAVFCGLLWWIAFHMRDRPLVIA
TLICLVTSQVISYIKARAEASGLRGDGGFIERPERLIIVLTGAGVSDFPFVPWPPALSVG
MWLLAVASVITCVQRLHTVWTSPGAIDRMAIPGKGDR*

Genomic Sequence

>Rv2612c
ATGAGCAAGCTGCCCTTCCTGTCCCGGGCGGCGTTCGCCCGGATTACCACCCCGATCGCC
AGGGGACTGCTGCGGGTCGGCCTCACGCCGGACGTCGTCACCATCCTGGGCACCACCGCG
TCGGTGGCGGGAGCGCTGACGCTGTTCCCGATGGGCAAGCTGTTCGCGGGTGCGTGTGTG
GTGTGGTTCTTCGTGTTGTTCGACATGCTGGACGGGGCGATGGCCCGGGAGCGCGGGGGC
GGCACTCGCTTCGGCGCGGTGCTGGACGCCACCTGTGACCGCATCAGTGACGGCGCGGTG
TTCTGCGGTCTGCTGTGGTGGATAGCGTTTCACATGCGCGACCGACCGCTGGTGATCGCG
ACCTTGATCTGTCTGGTCACCTCGCAGGTGATCTCTTACATCAAGGCCCGGGCGGAGGCC
AGCGGGCTGCGCGGCGACGGCGGCTTCATCGAACGGCCGGAACGGTTGATCATCGTGCTG
ACCGGCGCCGGGGTGTCGGACTTCCCGTTTGTGCCCTGGCCGCCGGCGTTGTCGGTGGGG
ATGTGGCTGCTGGCCGTCGCCAGCGTGATCACCTGCGTGCAGCGGTTGCACACGGTCTGG
ACTTCACCCGGAGCCATCGATCGGATGGCGATTCCTGGAAAGGGCGACCGGTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv2710	active	shahanup86	2012-10-05
	Co-expression (Functional linkage) JH. Lee, PC. Karakousis et al. Roles of SigB and SigF in the Mycobacterium tuberculosis sigma factor network. J. Bacteriol. 2008
Interaction	RegulatedBy Rv2710	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. JH. Lee, PC. Karakousis et al. Roles of SigB and SigF in the Mycobacterium tuberculosis sigma factor network. J. Bacteriol. 2008
Name	Phosphatidyl-myo-inositol synthase and/or phosphatidyl-myo-inositol phosphate synthase	active	mjackson	2012-10-05
	Phospholipid biosynthesis
Name	Phosphatidyl-myo-inositol synthase and/or phosphatidyl-myo-inositol phosphate synthase	active	mjackson	2012-10-05
	Phospholipid biosynthesis
Term	TBPWY:Phospholipid-Biosynthesis Phospholipid Biosynthesis - NR	active	mjackson	2012-03-05
	Phosphatidyl-myo-inositol synthase and/or phosphatidyl-myo-inositol phosphate synthase (phenotypic [mycobacterial recombinant strains]; enzymatic) authors,H. Morii,M. Ogawa,K. Fukuda,H. Taniguchi,Y. Koga A revised biosynthetic pathway for phosphatidylinositol in Mycobacteria. J. Biochem. 2010
Term	TBPWY:Phospholipid-Biosynthesis Phospholipid Biosynthesis - NR	active	mjackson	2012-03-05
	Phosphatidyl-myo-inositol synthase and/or phosphatidyl-myo-inositol phosphate synthase (phenotypic [mycobacterial recombinant strains]; enzymatic) M. Jackson,DC. Crick,PJ. Brennan Phosphatidylinositol is an essential phospholipid of mycobacteria. J. Biol. Chem. 2000